The Department of General Surgery has a long tradition in translational research. Problems encountered in the daily clinical care of patients are translated into research questions that are experimentally addressed in our laboratories using patient-derived materials and/or via small interventions during surgery. Insights gained from these studies aim to improve patient care and treatment options of patients. Basic and translational research at our department focuses on disorders of the intestines and hepatopancreatobiliary system. This research is done in the metabolic and immunological field. Presently, it is recognized that integration of both fields is required to gain a more complete picture of these disorders.